The Phytochemical investigation was carried out on the crude chloroform and methanol extracts of the aerial parts of Viburnum punctatum (Caprifoliaceae). The antimicrobial activity of the extract was tested against chemical isolates of some bacteria using the disc diffusion method. The preliminary phytochemical studies revealed the presence of alkaloids, glycosides, flavonoids, fixed oils and fats, phenolic compounds and tannins, proteins and aminoacids, gums and mucilage, phytosterols and saponins as chemical class present in the extracts. The extracts showed inhibitory activity against clinical isolates of the gram positive bacteria such as Salmonella typhi, Klebsiella pneumonia, Staphylococcus aureus, gram negative bactria is Escherichia coli and Candida albicans. The results showed that the methanol extract was more potent than the chloroform extract.