Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2016 Vol: 8 Issue: 2

Phytochemical and pharmacological screening of in vivo anti-inflammatory activity of Aegle marmelos(L.) Corr. Serr.

Abstract

The aim of this study is to evaluate anti-inflammatory activity and to determine phytochemical constituent of ethanolic leaf extract of Aegle marmelos(L.) Corr. Serr.. Plant materials are collected from Punjab. Ethanolic extract was screened for different phytochemical constituents. Acute toxicity studies are done according to OECD guidelines. Ethanolic extracts were screened for anti-inflammatory activity (induced by Carrageenan) in Wistar Albino rats. Ethanolic extract Aegle marmelos(L.) Corr. Serr. Shows significant anti-inflammatory activity compared to control. Presence of alkaloid, saponins and steroids were identified in the extract. The result suggests that the ethanolic extract of Aegle marmelos(L.) Corr. Serr. contains some active principles which may possess significant anti-inflammatory activity.