A surface modified CdHCF film electrode using cys-Au nanoparticles mixed graphite was prepared to resolve the paracetamol (pH 7). The voltammetric behaviour of the CdHCF customized electrode incidence in different alkali metal cations was investigated by electrochemical instrument. It’s also characterized using impedance spectroscopy. Surface of the electrode was characterized by Transmission electron microscopy (TEM) it’s represent that the modified surface of the CdHCF particles were discrete homogeneously on the electrode surface in the range of 10-15 nm. The modified surface is exhibiting good catalytic response on paracetamol sensor with high solidity and reproducibility. The Potential of oxidation towards paracetamol in differential pulse voltammetry was lowered 110mV and ampere response was enhanced significantly relative to a bare electrode. 7.2X10-7 to 2.6X10-3M range was observed in linear calibration curve for paracetamol sensor with 0.999 correlation coefficient. The exposure frontier anticipated to be 2.4 X10-8 M. The common interferents viz., ascorbic acid, dopamine and uric acid did not affect the determination of paracetamol significantly. This method is illustrated by sensing paracetamol in pharmaceutical preparations.