Calendula officinalis, belonging to the family of Asteraceae, commonly known as English marigold or Pot Marigold is an aromatic herb which is used in Traditional system of medicine. It is mainly used because of its various biological activities to treat diseases like analgesic, antidiabetic and anti-inflammatory. It is also used for ingastro-intestinal, gynaecological, eye disease, skin injuries and in some cases of burn. This plant is rich in many pharmaceutical active ingredients like cartenoids, flavonoids, glycosides, steroids and sterols quinines, volatile oil, and amino acid. The extract of this plant as well as pure compound isolated from it, have been demonstrated to possess multiple pharmacological activities such as anti-HIV, cytotoxic, antiinflammatory, hepatoprotective and spamolytic amongst others. In this review, we have explored the organoleptic, in-vitro and in-vivo pharmacological activities of Calendula officinalis in order to existing information on this plant as well as highlight its multiactivity properties as a medicinal agent.