The need for delivering drugs to patients efficiently with minimum side effects has prompted pharmaceutical industries to be engaged in development of new drug delivery systems. Pediatric and geriatric patients find it difficult to swallow solid dosage forms like tablets. Oral dispersible tablet is solid unit dosage form. The objective of present investigation was to prepared oral dispersible tablet of Levocetirizine Dihydrochloride and Montelukast Sodium because it’s active working patients who are busy or travelling, especially those who have no access to water. This review depicts the various aspects of ODT formulation, superdisintegrants and technologies developed for ODT, along with various drugs explored, evaluation tests and marketed formulations in this field. Oral Dispersible tablets are prepared they are required to be evaluated for various parameters.