Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2014 Vol: 6 Issue: 8

Optimization and validation of a method for determination of ibuprofen by HPLC in different pharmaceutical forms: Tablet, syrup, gel and suppository

Abstract

A simple, fast, economical, accurate, precise and reproducible RP – HPLC method was developed for the determination of Ibuprofen. The method was validated in terms of specificity, linearity, precision accuracy, and robustness. The proposed method’s results were found to be satisfactory and are suitable for determination of Ibuprofen for routine quality control of drugs in bulk drug and formulation.