Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 7

One-Pot, Four-component Synthesis of Oxime ethers from Cinnamaldehyde, Crotonaldehyde, Hydroxylamine Salt, Potasium carbonate and Alkyl halides

Abstract

Oxime ethers were synthesised in a one-pot, four-component reaction from cinnamaldehyde crotonaldehyde, hydroxylamine hydrochloride, anhydrous sodium carbonate and some alkyl halides. Alkyl halides also served as the solvent of the reaction. The reactions were completed in about 1 hour with yields of 57 to 84%.