The present work is mainly designed to synthesize a variety of new 2,3-dihydro-1H-1,5- benzodiazepine derivatives using symmetrical and unsymmetrical diamines and substituted ketones to obtain number of 1,5-benzodiazepine derivatives catalyzed by anhydrous stannous chloride. The proposed mechanism of this reaction involves an intramolecular imine enamine cyclization promoted by stannous chloride anhydrous. The remarkable advantages offered by this method are easily and inexpensive available catalyst, simple procedure, mild conditions, much faster (40–60 min) reactions and moderate to good yields of products.