Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2010 Vol: 2 Issue: 4

One pot high yield synthesis of some novel isoxazolidine derivatives using Nmethyl- ?±-chloro nitrone in water and their antibacterial activity


A simple one pot and high yield efficient method is described in water for the diastereo and regioselective synthesis of some novel isoxazolidine derivatives at room temperature in a short reaction time. All the novel isoxazolidines have been screened for antimicrobial activity and found to be very active