Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 4

Nano TiO2: A recyclable catalyst for one pot synthesis of 2-(substituted phenyl) phthalazin-1(2H)-one

Abstract

We have developed an efficient protocol for synthesis of 2-(substituted phenyl) phthalazin-1(2H)-ones from Phthalaldehydic acid, substituted phenyl hydrazine using Nano TiO2 as a catalyst. Simplicity, short reaction time, easy work up, cheap catalyst, good yield are the major advantages of the proposed method.