Organocatalysis is going to be an art in Synthetic Green Chemistry and Synthesis manly stated to be used for accelerating the rate of chemical reaction with a substoichiometric amount of an organic compounds which does not contain a metal atom [1,2]. It has developed into a practical synthetic paradigm. The area of as a L-Proline organocatalysis has been one of the most dynamic and rapidly growing fields in organic synthesis over the last decade, largely due to its great potential for realizing highly complex, effective , selective asymmetric transformations and amine derivatives also used for various reactions such as asymmetric Aldol condensation , asymmetric Michael reaction, organocatalytic H activation, asymmetric anti 1,2 diol, epoxide formation, transamination, Mannich reactions, asymmetric α- hydroxyamination, polymerization, One pot Multi-component reactions and in synthesis of some class of flavanoid molecules. This review article provides update information on recent reports and explains usefulness of L-Proline organocatalysis and its efficiency for this approach and scope. The data on the methods of synthesis, chemical reactions, and work on this in various publications over the last decade are reviewed here.