Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2016 Vol: 8 Issue: 12

Microwave Assisted Improved Method for the Synthesis, Characterization of N- Aroyl -3,5-disubstituted Pyrazoles


The present research has systematic approach to synthesized a series of 1- phenyl-4-yl-methanone-3,5-disubstituted Pyrazoles ( 3a-d) and 1- pyridine-4-yl-methanone-3,5-disubstituted pyrazoles ( 5a-c ) derivatives by the action of substituted 1,3-disubstituted propane-1,3-diones with phenyl hydrazide and isoniazide respectively. The compounds were synthesized by green chemistry technique. Structures of all the synthesized compounds were confirmed by their IR, 1H-NMR.