Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 5

Lipases-catalyzed enantioselective kinetic resolution of alcohols

Abstract

The purpose of this brief review is to report overviews of the state of art in the kinetic resolution of racemic alcohols using lipases. This review includes types of lipases, function, and applications in organic synthesis, as well as their mechanism in hydrolysis of esters. Moreover the review highlight success stories about the separation of different alcohols racemates explaining the advantages of the methods employed. A particular attention was drawn to the literature published within the period from 2010 upwards to June 2015.