Bacteria play a major role in the biogeochemical cy cling of toxic heavy metals. Heavy metal resistant bacteria can be used as bioremediation agents. The aim of this p resent investigation was to determine the resistanc e property of bacteria isolated from industrial waste dumped soil samples, to heavy metals (Pb 2+ and Cd 2+ ) and some antibiotics. Of 29 isolates, only two bacterial strains were fou nd to be highly resistant to lead and cadmium. Furt her, these two bacterial strains were checked for resistance again st heavy metals by culturing them in basal medium i n which varying concentrations of heavy metals were incorpo rated. HML8 and HMC1 isolates showed resistance aga inst Pb 2+ and Cd 2+ at all concentrations tested. The morphological an d biochemical tests confirmed that the isolates belonged to Bacillus sp. Both the isolates showed s imilar pattern of growth at different temperature r anging from 25 ⁰ C to 42 ⁰ C. HMC1 showed better growth in the presence of hig h NaCl concentration but the same was unable to grow at high pH. On the other hand HML8 showed good growth in the basal medium at high pH. High salt concentration affected the growth of HML8 in the ba sal medium. Both the isolates also exhibited high t olerance to antibiotics such as Amoxicillin and Penicillin G. T he results of the present study clearly suggest tha t both the strains can be studied and explored further for biotechnolo gical applications especially for lead and cadmium detoxification.