Increasingly as a result of better distribution channels, urbanisation in lower-middle income countries, and pandemic's long-lasting consequences. The formulation of Active Pharmaceutical Ingredients (APIs), the drug ingredients that result in the desired biological impact, is the primary focus of the upstream industry. Then, these goods are divided according to product segments [1]. The pharmaceutical industry has had the greatest growth in demand for analgesics during the past three years [2]. Both prescription and over-the-counter versions of these medications are available to relieve pain and reduce inflammation [3]. One of the most popular over-the-counter medications on the market, the API paracetamol, was the focus of this study. Acetaminophen has an anti-inflammatory action and is therefore prescribed for a broad range of chronic diseases and a myriad of clinical problems, which accounts for its high demand. Acetaminophen is produced as a powder [4]. Then, this powder is made into tablets, capsules, liquid solutions, or intravenous fluids. Around 80,000 metric tonnes of the bulk analgesics' paracetamol component are produced annually, with an estimated worth of $400 million. This estimate takes into account the global market availability price range of $3.5 to $5 [5].