Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 7

Isolation of flavonoids and biological activities of Crotalaria Grahamiana


The flavonoids of Crotalaria grahamiana (family Pop ilionaceae) were isolated from the alcoholic extrac t by partition with benzene, diethyl ether, ethyl acetat e respectively. On the basis of chemical and spectr al analysis their structures are elucidated as 4’hydroxy flavone-7-O- rhamnoside and its aglycone.Identification of unkno wn compounds were established through comparison of ch romatographic and spectral data (PC, UV, and NMR) w ith literature values. Isolated yellow pigment for furt her studies was promoted to anti-microbial and SRBC membrane stabilization. It reveals that isolated compound sh ows significant antimicrobial and anti inflammatory activity.