Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2014 Vol: 6 Issue: 4

Influence of compatibility of uncaria ramulus cumuncis with gastrodia rhizoma on liver gene expression in SHR rats

Abstract

Study the influence of compatibility of Uncaria Ramulus Cum uncis with Gastrodia Rhizoma on Liver Gene Expression in SHR Rats. Four SHR rat groups were established, including Blank, Uncaria decoction, Gastrodia suspension, Gastrodia and Uncaria decoction combined. After 10 days of continuous oral administration, mRNA in the liver of SHR rats was extracted, and then was hybrided with gene chip. After computerized scanning and analyzing, the changes in gene expression were observed. Fifteen target genes before and after compatibility of Uncaria Ramulus Cum uncis with Gastrodia Rhizoma were selected out.