Groundwater samples collected during November 2009 - February 2010 from five different locations in Amalner town were subjected to comprehensive physicochemical analysis. Water quality index (WQI) values were computed to assess the groundwater with respect to drinking purpose. Groundwater samples from Shivaji Nagar, Dheku road and Weekly market indicated good water quality and fit for drinking purpose. The ground water samples from Shirud naka and Cotton market showed poor water quality as reflected by WQI value. The poor water quality has been found mainly due to higher values of EC, TDS, TA, TH and Cl- in ground water.