The aim of the study was to investigate the stem bark Extracts of Senna alata phytochemical compounds of ethanol extract. The phyto compounds were screened by qualitative and GC-MS method. Qualitatively the different extracts were analyzed the compounds were found to like alkaloids, saponins flavonoids, tannins, glycosides, whereas reducing sugar, quinines, and coumarins, totally absent in this plant. In the GC-MS analysis, 22 bioactive compounds were identified in the ethanol extract of stem bark of Senna alata.