GC-MS analysis was carried out for the identification of the phytochemicals present in the methanolic leaf extract of .Nothapodytes nimmoniana. It indicates that the leaf extract is rich in phenolics, fatty acids, flavonoids and antioxidants. GC-MS analysis of methanol extract to identification of 26 compounds. The main compounds, were 9,12,15-Octadecatrienoic acid, [Z,Z,Z] is a compound name Linolenic acid used for Antiinflammatory, antiarthritic, anticoronary and anticancer,etc.