Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

header
Reach Us reach to JOCPR whatsapp-JOCPR +44 1625708989
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Original Articles: 2017 Vol: 9 Issue: 9

Formulation and Evaluation of Zolmitriptan Oro Flash Films

Abstract

The present study was aimed to formulate and evaluate fast dissolving oral films of Zolmitriptan using propylene glycol, HPMC-E50 LV and sodium starch glycolate. The suitable plasticizer and its concentration were selected based on flexibility, tensile strength and stickiness of the film. The films are prepared by solvent casting method and characterized by UV, FTIR studies. The films were evaluated for SEM, disintegration time, Folding endurance, Tensile Strength, Mouth dissolving time, Thickness, content uniformity and in vitro dissolution studies.