Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 6

Facile Three-component Synthesis of imidazo[4,5-b]indoles


A rapid, efficient and high yielding synthetic procedure to 3,4-dihydro-2-arylimidazo[4,5- b]indole by the multicomponent reaction of aromatic aldehydes, indoline-2,3-dione and ammonium acetate catalyzed by L-proline under ultrasonic irradiation is described.