Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 2

Evolution of Free Radical Scavenging Potential of Embelia Basal

Abstract

Reactive Oxygen Species (ROS) is a metabolic side product of oxidative stress process which causes several diseases like atherosclerosis, cancer etc. In defense of ROS, antioxidants play a key role in combating them. Plant products, phenolics and flavonoids serve a best source for controlling these activities by its own metabolic pathway. Thus in this aspect the spectrophotometric determination of phenolics and flavonoids content from acetone, ethanol and methanol extracts of fruits of Embelia basal using Folin –Ciocalteau reagent and Quercetin as standard were carried out. The results show high contents of phenolics and flavonoids which are responsible for the antioxidant activity of the plant. Considering the above facts plant extracts further screened in-vitro, for their possible radical scavenging antioxidant activity by employing 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) and total reducing power with ascorbic acid as a standard. The results of the present study revealed that the fruit extracts of E. basal can be a potential source of natural antioxidant, which can be applied as new source of Antioxidant Activity Index (AAI).