Original Articles: 2014 Vol: 6 Issue: 6
Evaluation of free radical scavenging potential of plant part extracts of medicinal plant- Aglaia lawii
Phytochemical investigation of Aglaia lawii leaves showed presence of flavonoids, carbohydrates, phenolics, triterpenoids, tannins etc. An attempt made to perform free radical scavenging potential of A. lawii's different parts. Free radicals are well documented for playing role in our body. Excess production of free radicals leads to oxidative stress in body. It results in pathological manifestations as atherosclerosis, cancer, inflammatory condition, diabetes, alzheimer’s disease Parkinson’s disease etc. A variety of synthetic medicines employed in the treatment of different diseases that are capable to generate free radicals in body which may cause another disease. In Ayurveda, the plant sources are rich of antioxidants. Phyto-constituents are capable to terminate free radical reactions and prevent body from oxidative damage with less side effects and compatible to body physiology. Considering the above facts present work deals with evaluation of free radical scavenging potential of A. lawii plant. The extracts of leaves, bark, stem and seed were screened in- vitro, for their possible radical scavenging antioxidant activity by employing 2, 2-diphenyl-1- picryl-hydrazyl (DPPH) and nitric oxide (NO) reducing power with ascorbic acid as standard. The results revealed that ethanolic extract of leaves, bark, stem and seed can be a potential source of natural antioxidant, which can be applied as new source of Antioxidant Activity Index (AAI) which may complete demand of modern era to use such phytoconstituents or phytomedicines. The data obtained in these testing systems clearly established the antioxidant potency of the plant.