Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 6

Evaluation of diuretic activity of Sida spinosa linn leaves extract


Aqueous and alcoholic extracts of Sida spinosa leaves were tested for diuretic activity in rats. The parameters studied on individual rat were body weight before and after test period, total urine volume, urine concentration of Na+, K- and Cl-. In the present study alcoholic and aqueous extracts of Sida spinosa leaves (100mg/kg of body weight) showed increase in urine volume, cation and anion excretion. Furosemide was used as reference diuretic.