Medicinal plants are the part and parcel of human society to combat against different diseases from the dawn of human civilization. According to World Health Organization, approximately 80% population of the developing countries are facing difficulties to afford synthetic drugs and are relying on traditional medicines mainly of plant origin in order to maintain their primary health care needs. Trigonella foenum -graecum Linn. Leguminosae, a seed spice used to enhance flavor, color and texture of food, and for medicinal purposes in many traditional systems. A number of epidemiological studies and laboratory research have revealed the biological actions of fenugreek. The anti-inflammatory and antipyretic effect of the acetonic extract of Trigonella foenum graecum was investigated. The anti-inflammatory effect was studied using Plethysmometer, while the antipyretic effect was estimated using Brewer's yeast-induced hyperpyrexia in rats. The results revealed that oral administration of AETFG at 50mg/Kg exhibited anti-pyretic effect comparable to the standard aspirin (100mg/kg). The plant extract not showed anti-inflammatory property.