Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

header
Reach Us reach to JOCPR whatsapp-JOCPR +44 1625708989
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Original Articles: 2014 Vol: 6 Issue: 8

Evaluation of antibacterial activity of extracts from Calendula aventis flowers

Abstract

Calendula arvensis (C.A.) is one of the herbs used in traditional medicine in Morocco , Due to its essential oil it is recognized by its smell and warmth characteristic .This work aims to evaluate the antibacterial activity of C.A. flower extracts , Hexanolic and methanolic extracts were obtained by the method of soxhlet , while aqueous extract was obtained by maceration in cold water. Antibacterial activity screening was conducted by the well diffusion method according to the clinical and laboratory standard institute guidelines using 6 Gram positive and 7 Gram negative bacteria (sensitive and multidrug-resistant) .The results indicated that , the methanolic extracts of C.A. flowers generally showed high inhibitory activity against Gram-positive and Gram negative bacteria except Acinetobacter baumanii , Proteus mirabilis and Listeria monocytogenes, The C.A. flowers hexanolic extract inhibited all bacteria of Gram-positive and Gram negative bacteria except, Staphylococcus aureus MRSA, Streptococcus agalactiae and Acinetobacter baumanii , There were no inhibitory effects of the aqueous extracts against all tested bacterial strains except Rhodococcuss equi and Morganella morganii, MICs values of methanolic extracts were between 12.5-25μg/ml . while MICs of values of hexanolic extracts were between 6.25- 12.5 μg/ml . In conclusion , the obtained results show an antibacterial potency of organic extracts of C.A. flowers. C.A. flowers Hexanolic extracts were bactericidal for most bacteria while methanolic extracts were bacteriostatic .

http://sacs17.amberton.edu/

rtp slot demo