The study aimed to verify the Schistosomiasis epidemiological behavior in the second largest city in the state of Alagoas-Brazil, Arapiraca, from 2010 to 2014, as well as understand the existing water collections contaminated by Biomphalaria genus snail. Secondary data collected in the Zoonosis Control Center were used, through the municipal Schistosomiasis Control Program. The study was approved by the Ethics Committee on September 3, 2015, under registration number 1.214.466. During the period studied, 44.000 results of parasitological examinations were analyzed, carried out by the Kato-Katz technique in a broad manner, that is, no restrictions in age, gender, race or other variables. Thereby, 1.953 positive cases of schistosomiasis were found, and the year 2012 presented the highest incidence of the disease; individuals aged from 16 to 20 years were the most affected by the parasite and the male gender was the most affected with 69% of cases. Regarding the 1.566 water collections analyzed, 285 were contaminated, however, only 116 were properly treated. It is noticed that the Schistosomiasis Control Program in the city of Arapiraca still works incipiently, and the schistosomiasis should be seen not only as a public health matter, but also as a social issue, where multidisciplinary activities must be seen as a priority by all governmental fields, investing in rural basic sanitation, health education and monitoring of infected individuals, thereby avoiding new outbreaks.