Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2013 Vol: 5 Issue: 5

EDTA-catalyzed fast and efficient eco-friendly synthesis of dicoumarol derivatives in water

Abstract

EDTA-Catalyzed a simple, fast and efficient eco-friendly green protocol for the synthesis of dicoumarol derivatives in excellent yields in water at room temperature. This EDTA-catalyzed aqueous reactions of 4-hydroxycoumarin and various aldehydes avoids the use of expansive, corrosive, toxic solvents and provides several advantages such as short reaction time and scalable green synthesis.