Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2016 Vol: 8 Issue: 3

Different HPLC analysis method of itraconazole

Abstract

The present review article deals with the method developed for itraconazole by HPLC method. A wide variety of columns, mobile phase combinations, degassers used for the study. Different flow rates where adjusted for mobile phase combinations. In some methods forced degradation studies was also carried out and the methods developed were validated according to the ICH guidelines. After studying different research articles it came to light that HPLC method development of itraconazole has been done in different dosage forms of itraconazole and still there is huge potential for new methods to be developed with different mobile phase and column combinations. These new method data are required by regulatory agencies

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