A simple and sensitive spectrophotometric method has been described for the assay of pantoprazole either in pure form or in pharmaceutical solid dosage form. Absorption maxima of Pantoprazole in water were found to be at 292 nm. Beer’s law is obeyed in the range 5-70 μg/mL. Result of percentage recovery and placebo interference shows that the method was not affected by the presence of common excipients. The percentages assay of Pantoprazole in tablet was more than 99%. The method was validated by determining its sensitivity, accuracy and precision which proves suitability of the developed method for the routine estimation of pantoprazole in bulk and solid dosage form.