Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 3

Development and Evaluation of Herbal Laxative Granules

Abstract

Sterculia gum is a complex polysaccharide of high molecular weight. The rapid swelling of gum particles, their relative insolubility and their unusual resistance to bacterial and enzymatic breakdown make this gum suitable as a bulk laxative. The present work deals with development of granular formulation using Sterculia gum and its evaluation. The evaluation includes size gradation using sieve analysis, granular friability, percent compressibility (Carr’s Index) and swelling Index. The present formulation was found to be comparable with other marketed laxative formulations containing Isapgol husk

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