Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 5

Determination of Tamsulosin in bulk and pharmaceutical dosage forms by UV spectrophotometric method

Abstract

A Simple, rapid, accurate and economical UV Spectrophotometric method is developed for determination of tamsulosin in bulk and pharmaceutical dosage forms. In methanol, the λmax of the drug was found to be 224 nm. Using UV instrument (analytical), in this proposed method tamsulosin follows linearity in the concentration range 1 – 5μg/ml with a correlation coefficient of 0.9989. Assay results were in good agreement with label claim. The methods were validated statistically and by recovery studies. The relative standard deviation was found to be 0.23516 with excellent precision and accuracy