Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2011 Vol: 3 Issue: 6

Copper(II), Nickel(II), Cobalt(II), Lithium(I) Complexes of thiosemicarbazide derivatives and Antibacterial activity


A new series of Copper(II), Nickel(II), Cobalt(II) and Lithium(I) complexes of 2- (phenylaminoactetyl-N-phenyl hydrazine carbothioamide(H2L) were prepared and characterized by IR, elemental analysis, H NMR spectroscopy, magnetic susceptibilities, electronic spectra and antibacterial activity . The ligand behaves as a neutral bidentate in coordination. This coordination takes place via the carbonyl oxygen of (C=O) and nitrogen atom of the N(2)H group in all complexes. Results showed that these medicaly important complexes had positive effects against some pathogenic bacteria including gram positive bacteria and gram negative bacteria that are pathogenic to human and animals

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