Pharmaceutical industries are widely been used for the production of wide range of antibiotics, solvents and many by-products which are widely useful for both man-kind and in agriculture purpose. The waste materials may be in the form of solids, liquids and gases and are been released in streams, soils and many are been vaporised into air from centuries, which are causing many hazardous to the human life and effecting the environment. Pharmaceutical industries are employing various methods for the treatment of waste which includes physical, chemical and mechanical methods but failed to reduce the toxicity and there is limited reduction in COD levels. So for the reuse of the waste water an advanced technology has been developed and research is going on still for better result known as Bioremediation which is an efficient and cost-effective treatment method for the cleanup of contaminated soils/water. The present study is aimed to treat the industrial effluents in the production of by products in drug manufacturing to reduce the COD, TSS, TDS and sulphates by the process of bioremediation.