Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 6

Clinicalcomparison of plain Chlorhexidine (0.2%) and Chlorhexidine (0.2%) in combinationwith Sodium Fluoride (0.05%) and Zinc Chloride (0.09%)


Numerous mouthrinses are available commercially to control gingival & periodontal diseases. This study was aimed to compare the efficacy of 0.2% Chlorhexidine and 0.2% Chlorhexidine in combination with 0.05% NaF& 0.09% ZnCl2. 50 subjects of both genders, aged between 18-32 years were selected for the study. They had undergone professional scaling, just before the trial of both mouthrinses. There was an experimental period of 2 months each & a washout period of 1 month in between the trials. They were examined clinically at each month from the baseline, till 2 months. The study results showed significant improvement in the plaque & gingival index scores at the end of 2 months, when compared with the baseline values. Comparative analysis between both the products showed statistically insignificant clinical results. Thus it is clear from the observed results that clinical effect of both the mouthrinses is almost same. The present study does not reveal any significant difference between both the products.