Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2016 Vol: 8 Issue: 6

Chromatographic and Mass Spectrometric Analysis of Antidiabetic Biopharmaceuticals


In the present communication various chromatography and chromatography coupled mass spectrometric methods used for the routine analysis of antidiabetic biopharmaceuticals such as insulin and its analogs were reviewed. The study revealed the fact that High Performance Liquid Chromatography (HPLC) was extensively used for quality control analysis of insulin and its analogs and mass spectrometric technique was widely used for the identification of impurities.