Achillea eriophora DC. is known locally as “Bumadaran-e- shirazi” or “Sàrzàrdu”, in Fars Province- Iran. It is a specific endemic medicinal plant in this area. GC-MS analysis of essential oil hydrodistilled from their aerial part obtained from Fasa city (Fars Province)-Iran, resolved into 46 compounds representing 99.58% of the essential oil. The chemical analysis of Sàrzàrdu, revealed the most abundant component was 1, 8-Cineole (16.772%) and the other major compounds of the oil were, Borneol, β-Phellandrene, Camphor, α-Pinene, δ-3-Carene and β-pinene with amounts of 16.169, 15.288, 9.771, 4.361, 3.986 and 3.902% of the total oil, respectively. Information about the essential oil composition assists us for estimate the quality of oils intended to their specific uses.