Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Reviews: 2016 Vol: 8 Issue: 8

Cancer in females: Are hormones the culprit?

Abstract

Hormones are small chemical messengers that play a major role in the human body which helps in regulation, control of growth, development, reproduction, maintenance of internal environment and energy production. Genomic and non-genomic signaling mechanisms make hormones take special care in maintaining their concentration in serum and plasma. Women are highly prone to the hormonal imbalance due to many factors such as diet, sexual activity, endocrine disruptors and reproductive behavior. Dysregulation and irregular function of these hormones lead to the development of many diseases from cyst formation to cancer development. Hence it is necessary to understand the role and mechanisms of hormonal actions in cancer cells to target them as novel biomarkers for therapeutic strategies.