Lagochilus macracanthus was the endemic species of Labiatae family in Iran. In this study the morphological and micromorphological structure of vegetative and reproductive organs, nutlet, pollen and anatomical structure of leaves and trichomes micromorphology of stems, leaves, calyx and spines were survived with light microscope and scanning electron microscope. Variations in leaf shape in this species were existing. In the tip of leaves and calyx small spine could be seen. Pollen surface was reticulate with pores which produced by tectate exine structure. The seed of this species was elliptic nutlet that its dorsal surface was convex with outstanding decorations and ventral surface V shape with reticulate structure associated by micro pores on it. Leaf cross-section structure was isobilateral and the main vein vascular system was crescent shape. Nine different types of trichomes in vegetative and reproductive organs could be seen, which divided into two main groups of glandular and non-glandular (simplified) trichomes. Glandular trichomes were seen as: peltate, capitates and digitated and non-glandular hairs were uni or bi-celled with thin or thick wall.