The study aimed at using crudeperoxidases fromPortulacaoleracea, Sonchusoleraceus, Xanthium strumarium, Cyperusrotandus and Trianthemaportulacastrum for catalyzing degradation of phenolic compounds in wastewaters. The extracted crude enzymes were characterized and the efficiency of each one to degrade or detoxify the phenolic pollutants was tested. The tested enzymes showed a wide range of substrate specificityand different rates of enzymatic activities. It is evident that the peroxidases enzymes were very active towards most of the phenolic compounds. When using pyrogallol as substrate, the peroxidase from C. rotandus showed high specific activity (1.75 U/mg-1) and high Km value (4.19 mMpyrogallol). All extracts showed marked ability to degrade the phenolic pollutants in the tested wastewaters. The highest rate of degradation was noticed when crude peroxidase from C. rotandus was added to both industrial and synthetic wastewaters.This study revealed that C. rotandus is the most interesting source of peroxidase enzymes for the eliminating or reducing phenolic pollutants in wastewaters.