Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Reviews: 2011 Vol: 3 Issue: 6

Benzotriazole in medicinal chemistry: An overview


Benzotriazole is a bicyclic heterocyclic system consisting of three nitrogen atoms and fused benzene ring, shows wide range of biological and pharmacological activities. Benzotriazole can be synthesized using benzene-1,2-diamine and carboxylic acid. Benzotriazole posses wide spectrum of biological activities like including antibacterial, antifungal, antiviral, antiinflammatory, antihypertensive, analgesic properties. The present reviews attempted to gather the various developments in synthesis and biological activities of benzotriazole derivatives.