Atom economy is a fundamental concept in green synthesis in organic chemistry. It refers to the efficiency of a chemical reaction in utilizing the atoms present in the starting materials to form the desired product, while minimizing the generation of waste products. Its integration into reaction design and synthetic strategies can foster innovation while driving chemical processes towards environmental friendliness. A higher atom economy indicates a more sustainable and environmentally friendly reaction. This research article embarks on an exploration of atom-economical reactions within the realm of green chemistry. Various examples and methods are presented to illustrate the implementation of atom economy in organic synthesis. The atom-efficient reactions ranging from click chemistry to coupling reactions have been explained in this review.