Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2015 Vol: 7 Issue: 7

Asymmetric synthesis and spectroscopic characterization of various N-substituted phthaloyl and tosyl derivatives


A convenient and efficient synthesis of series of new optically pure N-substituted α-amino esters starting from 2- methoxy-4-(2-propenyl) phenol (eugenol) and natural amino acids is described. This improved procedure offers a convenient and effective method to access some interesting molecules containing phthalimide, tosyl and alkenes functionalities.

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