Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

Reach Us reach to JOCPR whatsapp-JOCPR +44 1625708989
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Original Articles: 2015 Vol: 7 Issue: 10

Assessment of nitrosative stress in Syrian patients with chronic periodontitis (Clinical laboratory study)


Nitrosative stress is considered to be a strong fea ture in chronic periodontitis, It was found that th e reactive nitrogen species (RNS) may play a role in periodnti tis either by being catalysts or they are in most cases aggravating factors of periodontal disease that i s already existing .The aim of this study is to examine the role of Nitrosative stress in periodontitis by assessing t he levels of RNS in gingival crevicular fluid (GCF) samples taken from Syrian patients with chronic periodontitis an d healthy controls. The study population comprised 35 subjects allocated within two groups: Chronic periodontitis (ChP) group (20 patients, aged 40-75) and Control g roup (RC) (15 subjects, aged 40-67). Nitrate/nitrite concentr ation in GCF was measured using Griess reagent. The re was no significant difference in Total nitrite/nitrate (GC F) levels between (ChP) and (RC) groups (P ˃ 0.05). Also, no significant correlations were found between the stu died marker and the periodontal indices (P ˃ 0.05) .The results of this study showed that the Nitrosative stress was n ot associated with chronic periodontitis in Syrian patients.