Principal Component Analysis (PCA) is a method to discriminant process a some active compound in herbal plants. The aims of this study were to compare the quality of ethanol extract of majapahit (Cresintia cujete), pegagan (Centella asiatica), and mangosteen rind (Garcinia mangostana) and also will determinant the discriminant between the herbal plants. Basic discriminant process were all component from active compound in the ethanol extract of the herbal plants. The results show that the discriminant process of ethanol extract from mangosteen rind, pegagan, and majapahit using Principal Component Analysis (PCA) can be distinguished. This discriminant result as an evidence for the active compound in the extract has different. This distinction is supported by the antioxidant activities of extract ethanol of mangosteen rind has antioxidant activity better than ethanol extract of pegagan and majapahit. The scavenging ability of DPPH from ethanol extract of mangosteen rind, pegagan and majapahit were 40.1 ug/mL, 172.1 ug/mL and 153 ug/mL respectively.