Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

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Original Articles: 2012 Vol: 4 Issue: 4

Application of pfitzinger reaction in the synthesis of quinoline-4-carboxylic acid derivatives of carbazolo and azacarbazolo fused indophenazine


Application of the Pfitzinger reaction on indophenazino fused carbazole 4a and azacarbazoles 4(b-e) with isatin (5) yielded the corresponding indophenazino fused quinoline-4-carboxylic acid derivatives 6(a-e) in moderate to good yield. All quinoline-4-carboxylic acid derivatives were characterized on the basis of their microanalysis IR, 1HNMR and MS spectral data.