Infection is one of the factors that most influence the wound healing retardation. The allocation of alternative resources to overcome the infection is essential for nurses, since they are responsible for the healing. This is an in vitro experimental study that investigated the antimicrobial, antioxidant and cytotoxic potential of crude extracts of plant species Tabebuia impetiginosa. The ethanolic leaf extract showed promising antimicrobial activity against Gram-positive strains of S. epidermidis (MIC ≥ 625 mg / mL) and S. aureus (MIC ≥ 312.5 mg / mL), demonstrating weak and moderate inhibitory activity, respectively. These same ethanol extracts of the leaves and twigs showed no cytotoxicity. These results provide evidence of safety in the therapeutic use of plant species so that future tests may be performed in vivo. This study highlights the expanded perspective on health, from the nursing context, as a way to promote technological innovation in infected wounds therapy. It is based on the achievement of experimental research, promoting the incorporation of new skills, knowledge and procedures for nursing science