Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)

Reach Us reach to JOCPR whatsapp-JOCPR +44 1625708989
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Original Articles: 2010 Vol: 2 Issue: 4

Antimicrobial Activity Of Thiosemicarbazone Derivatives Of Lawsone And Its Nickel Complexes


Thiosemicarbazone derivative at 1 and 2 position of the Biologically important Lawsone ( 2- hydroxy-1,4-naphthalenedione ) have been synthesized. This possesses a powerful chelating ability, appreciable analytical utility and significant biological activity. Metal complexes of TSCND with Ni(II) metal have been synthesized and studied with the help of spectral analysis and elemental analysis. The antimicrobial activity of the ligands and their metal complexes against bacteria and fungus has been carried out. It is found that the metal complexes have higher activities than those of free ligands