Nyctanthus Arbortristis Linn. is an medicinal plant having application in various disorders and have particular emphasis on potency specified in the screening assays. The present study was designed to evaluate the antiinflammatory and analgesic activities of the methanolic and chloroform extract of leaves of Nyctanthus Arbortristis Linn. (Family-Oleacea).The aim of the study is to access the anti-inflammatory activity against carrageenen induced Rat Paw oedema. The analgesic activity was determined for its central and pharmacological actions using Eddy’s Hot Plate, and Tail Immersion Method. Therefore, it concluded the methanolic and chloroform extract of the leaves of Nyctanthus Arbortristis possessing anti-inflammatory and analgesic activities.